Growth of XR122N (solid blue) and AJP50 (dashed black) in the presence of various mixtures of inhibitory compounds found in biomass fermentations. Growth in (A) the aromatic mixture; (B) the acid mixture; (C) a combination of hydroxymethylfurfural (HMF), furfural (FF), and acetic acid; and (D) the furan mixture. All compounds and their concentration in the media are shown in Table 2. The inhibitory compounds were dissolved in tryptic soy broth with 2% w/v glucose. Error bars represent one standard deviation from the mean. XR122N required a higher volume of revived culture to obtain a cell concentration equivalent to 4.0 × 105 cells/ml; this increased the wood particulate matter in the culture and led to the higher initial optical density seen in some XR122N cultures.
Hawkins and Doran-Peterson Biotechnology for Biofuels 2011 4:49 doi:10.1186/1754-6834-4-49